> ## Content Index > Fetch the complete content index at: https://www.jetsetteralerts.com/llms.txt > Use this file to discover other available public pages before exploring further. # Airlines With The Cheapest Flights from Chicago to South America - URL: https://www.jetsetteralerts.com/airlines-with-cheap-flights-from-chicago-to-south-america/ - Published: 2025-05-18T22:51:47.000Z - Updated: 2026-01-28T09:35:49.000Z - Description: Discover which airlines offer the best deal on flights from Chicago O'Hare International Airport to South America. - Author: Jetsetter Alerts - Tags: Budget Travel, Travel Blog, Airlines If you're searching for **which airlines have the cheapest flights from Chicago International Airport (ORD) to South America**, budget-friendly airlines like **Avianca**, **Copa Airlines**, **Spirit Airlines**, and **Aeromexico** consistently provide the most affordable fares to various South American cities either direct or via connection. --- ## Avianca ![Avianca aircraft descending with landing gear deployed, flying over green terrain with mountains in the background.](https://storage.ghost.io/c/b2/5a/b25ae1cc-57ff-42d2-b189-680f1dd95ffc/content/images/2025/05/Avianca-Flight-Landing-In-Colombia.jpg) [Avianca](https://www.avianca.com/en/) provides **affordable** direct flights from Chicago O'Hare International Airport (ORD) to Bogotá, Colombia. Travelers seeking budget-friendly flights can also access numerous other South American cities via a convenient one-stop connection through Bogotá: - Lima, Peru — one-stop via Bogotá - Quito, Ecuador — one-stop via Bogotá - Guayaquil, Ecuador — one-stop via Bogotá - La Paz, Bolivia — one-stop via Bogotá - Santa Cruz, Bolivia — one-stop via Bogotá Avianca’s extensive network and competitive pricing make it a top choice for cheap flights from Chicago to South America. ✈️ Not A Member? Save Up To 95% On Flights! Our Airline mistake fare and flash sales alerts allow our members to travel the world for a fraction of the flight cost. [View Flight Deals](https://www.jetsetteralerts.com/mistake-fare-examples/) ## Copa Airlines ![Copa Airlines aircraft on final approach for landing, flying over a hilly landscape with green vegetation.](https://storage.ghost.io/c/b2/5a/b25ae1cc-57ff-42d2-b189-680f1dd95ffc/content/images/2025/05/Copa-Airlines-Flight-Landing.jpg) [Copa Airlines](https://www.copaair.com/) offers budget-friendly direct flights from Chicago O'Hare International Airport (ORD) to Panama City, Panama. From Panama City, travelers can easily reach many **South American cities** through affordable one-stop connections: - Bogotá, Colombia — one-stop via Panama City - Lima, Peru — one-stop via Panama City - Quito, Ecuador — one-stop via Panama City - Guayaquil, Ecuador — one-stop via Panama City - Buenos Aires, Argentina — one-stop via Panama City - Santiago, Chile — one-stop via Panama City Copa Airlines provides reliable and cheap fares ideal for budget-conscious travelers flying from Chicago. --- ## Spirit Airlines ![ Bright yellow Spirit Airlines jet landing on a runway during daylight, with other planes visible in the background.](https://storage.ghost.io/c/b2/5a/b25ae1cc-57ff-42d2-b189-680f1dd95ffc/content/images/2025/05/Spirit-Airlines-Airplane.jpg) [Spirit Airlines](https://www.spirit.com) offers **low-cost flights** from Chicago O'Hare International Airport (ORD) to Fort Lauderdale. From Fort Lauderdale, budget travelers have affordable access to various South American destinations through convenient one-stop flights: - Lima, Peru — one-stop via Fort Lauderdale - Quito, Ecuador — one-stop via Fort Lauderdale - Guayaquil, Ecuador — one-stop via Fort Lauderdale - Bogotá, Colombia — one-stop via Fort Lauderdale - Medellín, Colombia — one-stop via Fort Lauderdale Spirit Airlines is a leading choice for travelers seeking the cheapest airfare options from Chicago. --- ## Aeromexico ![Aeromexico airplane in mid-flight against a clear blue sky, viewed from the side during descent.](https://storage.ghost.io/c/b2/5a/b25ae1cc-57ff-42d2-b189-680f1dd95ffc/content/images/2025/05/Aeromexico-Airlines-Landing-Approach.webp) [Aeromexico](https://www.aeromexico.com/) provides **cost-effective direct flights** from **Chicago O'Hare International Airport (ORD)** to Mexico City. Passengers looking for affordable flights can connect via Mexico City to **numerous South American destinations**: - Bogotá, Colombia — one-stop via Mexico City - Lima, Peru — one-stop via Mexico City - Quito, Ecuador — one-stop via Mexico City - Guayaquil, Ecuador — one-stop via Mexico City - Santiago, Chile — one-stop via Mexico City Aeromexico’s competitive pricing and extensive connectivity make it a popular option for cheap flights from Chicago. --- With these airlines offering budget-friendly flight options from Chicago O'Hare International Airport, finding an affordable flight to South America has never been easier. Sign up for [**cheap flight alerts**](https://jetsetteralerts.com), and be notified of the best flight deals to South America from airports near you. --- #### More On Cheap Flights To South America - [****Airlines With Cheapest Flights To South America**](https://www.jetsetteralerts.com/budget-friendly-airlines-offering-flights-from-us-to-south-america/) - [****Cheapest Airlines from Denver (DEN) To South America**](https://www.jetsetteralerts.com/airlines-with-the-cheapest-flights-from-denver-to-south-america/) - [****Cheapest Airlines From Chicago (ORD) to South America**](https://www.jetsetteralerts.com/airlines-with-cheap-flights-from-chicago-to-south-america/) - [****Airlines With Cheapest Flights From Orlando (MCO) to South America** ](https://www.jetsetteralerts.com/airlines-with-cheapest-flights-from-orlando-to-south-america/) ****Not A Member? ✈️** Save 40%-95% On Flights With Jetsetter Alerts Airline Mistake Fare & Flash Sales Alerts! [Get Personalized Airfare Alerts ](https://jetsetteralerts.com/mistake-fare-examples) [6 Cheapest Airlines from The U.S. to South AmericaDiscover which budget-friendly carriers offer the cheapest flights from the United States to South American cities.![](https://storage.ghost.io/c/b2/5a/b25ae1cc-57ff-42d2-b189-680f1dd95ffc/content/images/icon/Jetsetter-Club-Logo-JS-Darkmode--4--1555.png)Jetsetter AlertsJetsetter Alerts![](https://storage.ghost.io/c/b2/5a/b25ae1cc-57ff-42d2-b189-680f1dd95ffc/content/images/thumbnail/Illustration-showing-a-plane-flying-from-United-States-to-South-America.png)](https://www.jetsetteralerts.com/budget-friendly-airlines-offering-flights-from-us-to-south-america/)